Terapia profiláctica con corticoides en la prevención del edema laríngeo postextubación: Una revisión sistemática

Prophylactic therapy with corticosteroids in the prevention of post-extubation laryngeal edema: A systematic review

  • Elena Cristina Esono-Fernández Hospital Clínico Universitario Virgen de la Arrixaca (Murcia, España)
  • Manuel Piñero-Zapata Departamento de Enfermería. Universidad Católica de Murcia (UCAM) (Murcia, España)
  • Consolación Giménez-Piñero Hospital Vithas San José (Vitoria-Gasteiz, España)
  • Catalina Vera-Corbalán Departamento de Enfermería. Universidad Católica de Murcia (UCAM) (Murcia, España)
Palabras clave: Edema laríngeo, Extubación traqueal, Corticoesteroides, Prevención y control
Key-words: Laryngeal edema, Airway extubation, Corticosteroids, Prevention y control




1. Piepho T, Cavus E, Noppens R, Byhahn C, Dörges V, Zwissler B, et al. S1 guidelines on airway managerment: Guideline of the German Society of Anesthesiology and Intensive Care Medicine. Der Anaesthesist Suppl 1 2015;64(S1):27-40. Disponible en: https://link.springer.com/content/pdf/10.1007%2Fs00101-015-0109-4.pdf [acceso: 25/04/2018]
2. Popat M, Mitchell V, Dravid R, Patel A, Swampillai C, Higgs A, Difficult Airway Society Guidelines for the management of tracheal extubation: Management of tracheal extubation. Anesthesia 2012;67(3):318-40. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2044.2012.07075.x [acceso: 25/04/2018]
3. Gómez-Ríos MA; Gaitini L; Matter ; Somri M. Guías y algoritmos para el manejo de la vía aérea difícil. Revista Española de Anestesiología y Reanimación 2017;65(1):41-48. Disponible en: https://sci-hub.tw/https://doi.org/10.1016/j.redar.2017.07.009 [acceso: 25/04/2018]
4. Ajvadi, Fayavar A; Edwards, Michael J; Greenland, Keith B; Irwin, Michael G, van Zundert, Andre. Tracheal extubation: Strategies for predicting and managing extubation. Australasian Anaesthesia 2015;13-24. Disponible en: https://search.informit.com.au/browsePublication;py=2015;res=IELHEA;issn=1032-2515;iss=2015 [acceso: 25/04/2018]
5. Thille, Arnaud W; Cortés-Puch, Irene; Esteban, Andrés. Weaning from the ventilator and extubation in ICU: Current Opinion in Critical Care 2013;19(1):57-64. Disponible en: https://journals.lww.com/co-criticalcare/Fulltext/2013/02000/Weaning_from_the_ventilator_and_extubation_in_ICU.10.aspx#pdf-link [acceso: 25/04/2018]
6. Cavallone, Laura F; Vannucci, Andrea. Extubation of the Difficult Airway and Extubation Failure: Anesthesia & Analgesia 2013;116(2):368-383. Disponible en: https://journals.lww.com/anesthesia-analgesia/fulltext/2013/02000/Extubation_of_the_Difficult_Airway_and_Extubation.18.aspx [acceso: 25/04/2018]
7. Artime, Carlos A; Hagberg, Carin A. Tracheal Extubation. Respiratory Care 2014;59(6):991-1005. Disponible en: http://rc.rcjournal.com/content/respcare/59/6/991.full.pdf [acceso: 25/04/2018]
8. Kulkarni, Atul P; Vandana Agarwal. Extubation failure in intensive care unit: predictors and management. Indian journal of critical care medicine 2008;12(1):1-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760915/ [acceso: 25/04/2018]
9. Akira, Kuriyama; Noriyuki, Umakoshi; Rao, Sun. Prophylactic Corticosteroids for Prevention of Postextubation Stridor and Reintubation in Adults. CHEST Journal 2017;151(5):1002-10. Disponible en: https://sci-hub.tw/https://doi.org/10.1016/j.chest.2017.02.017 [acceso: 25/04/2018]
10. Pluijms, Wouter A; van Mook, Walther NKA; Wittekamp, Bastiaan HJ; Bergmans, Dennis CJJ. Postextubation laryngeal edema and stridor resulting in respiratoy failure in critically ill dault patien: updated review. Critical Care 2015;19(1):1-9. Disponible en: https://ccforum.biomedcentral.com/track/pdf/10.1186/s13054-015-1018-2 [acceso: 25/04/2018]
11. DeMuro, Jonas P; Mongelli, Michael N; Hanna, Adel F. Perioperative upper airway edema: Risk factors and management. Critical Care & Shock 2013;16(4):125-132. Disponible en: http://criticalcareshock.org/files/Perioperative-upper-airway-edema-Risk-factors-and-management.pdf [acceso: 26/04/2018]
12. Bittner, Edward A; Schmidt, Ulrich H. Tracheal Reintubation: Caused by ”Too Much of Good Thing”?. Respiratory Care 2012;57(10):1687-1691. Disponible en: http:// http://rc.rcjournal.com/content/respcare/57/10/1687.full.pdf [acceso: 25/04/2018]
13. Girard, Timothy D; Alhazzani, Waleed; Kress, John P; Ouellette; Daniel R; Schmidt, Gregory A; Truwit, Jonathon D, et al. An Official American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. Rehabilitation Protocols. Ventilator Liberation Protocols, and Cuff Leak Tests. American Journalof Respiratory and Critical Care Medicine 2017;195(1):120-133. Disponible en: http://www.atsjournals.org/doi/10.1164/rccm.201610-2075ST [acceso: 25/04/2018]
14. McCaffrey J, Farrell C, Whiting P, Dan A, Bagshaw SM, Delaney AP. Corticosteroids to prevent extubation failure: asystematic rewview and meta-analysis. Intensive Care Med 2009;35(6):977-86. Disponible en: http:// link.springer.com/10.1007/s00134-009-1473-9 [acceso: 25/04/2018]
15. Bagshaw, Sean M; Delaney, Anthony; Farrell, Clare; Drummond, Jennifer; Brindley, P eter G. Steroids to prevent post-extubation airway obstruction in adult critically ill patients. Canadian Journal of Anesthesia 2008; 55(6):382-385. Disponible en: https://link.springer.com/content/pdf/10.1007%2FBF03021496.pdf [acceso: 25/04/2018]
16. Sutherasan, Yuda; Theerawit, Pongdhep; Honghanut, Tanasit; Kiatboonsri, Charn; Kiatoboonsri, Sumalee. Predicting laryngeal edema in intubated parients by portable intensive care unit ultrasound. Journal of Critical Care 2013;28(5):675-680. Disponible en: https://sci-hub.tw/https://doi.org/10.1016/j.jcrc.2013.05.011 [acceso:18/09/2018]
17. Parotto, Matteo; Cooper, Richard M. Tracheal extubation and reintubation of the critically ill – challenges coming and going. Critical Care 2015;19:151. Disponible en: https://ccforum.biomedcentral.com/track/pdf/10.1186/s13054-015-0841-9 [acceso: 25/04/2018]
18. Windisch W, Karagiannidis C, Die schwierige Extubation. Medizinische Klinik- Intensivmedizin und Notfallmedizin 2012;107(7):537-542. Disponible en: https://sci-hub.tw/http://link.springer.com/10.1007/s00063-012-0091-4 [acceso: 25/04/2018]
19. Malhotra, Dinesh; Gurcoo, Showkat, Qazi, Shagufta, Gupta, Satyadev. Randomized Comparative Efficacy of Dexamethasone to Prevent Postextubation Upper Airway Complications in Children and Adults in ICU. Indian Journal of Anaesthesia 2009;53(4):442-449. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894502/ [acceso: 16/09/2018]
20. Emery, Sanford E; Akhavan, Sam; Miller, Pama, Furey, Christopher G; Yoo, Jung U; Rowbottom; James R, et al. Steroids and Risk Factors for Airway Compromise in Multilevel Cervical Corpectomy Patients: A Prospective, Randomized, Double-Blind Study. SPINE 2009;34(3):229-232. Disponible en: https://sci-hub.tw/10.1097/BRS.0b013e318193a287 [acceso: 16/09/2018]
21. Cheng KC, Chen CM, Tan CK, Chen HM, Lu CL, Zhang H. Methylprednisolone reduces the rates of postestubation stridor and reintubation associated whit attenuated cytokine responses in critically ill patients. Minervas Anestesiológica 2011;77(5):503-509. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929386/pdf/nihms3772.pdf [acceso: 16/09/2018]
22. Abbasi, Saeed; Moradi, Siamak; Talakoub; Reihanak; Kashefi, Parvitz; Koushki, Ali M. Effect of nebulized budesonide in preventing postextubation complications in critically patients: A prospective, randomized, doublé-blind, placebo-contolled study. Advanced Biomedical Research 2014;3(1):182. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166049/ [acceso: 16/09/2018]
23. Kashefi, Parvitz; Abbasi, Ali; Abbasi, Mahanaz; Davoodi, Leila; Abbasi, Saeed. Comparison of the efficacy of nebulized budesonide and intavenous dexamethasone administration before extubation in prevention of post-extubation complications among patients admitted in intensive care unit. Advanced Biomedical Research 2015;4(1):11. Disponible en: http://www.advbiores.net/temp/AdvBiomedRes4111-2414077_064220.pdf [acceso: 21/09/2018]
24. Lin, Chang-Yi; Cheng, Kuang-Hua; Kou, Li-Kuo; Lee, Chao-Hsien. Comparison of High – and Low –dose Dexamethasone for Preventing Posextubation Airway Obstruction in Adults: A Prospective, Randomized, Double blind, Placebo – controlled Study. International Journal of Gerontology 2016;10(1):11-16. https://reader.elsevier.com/reader/sd/pii/S1873959816000041?token=6DB2549219DFC60B42B5BF06B5586C34D379229FE91BA92FA5920151A80A83E310D8974EE1237D86BB4FAA2B7F3A5CAC [acceso: 17/05/2018]
25. Shaikh N, Mehesry T, Hussain G, Chanda A, Belkhair A, Sheikh S, Malmstrom F, Marcus AE. Use of Steroids for Extubation Failure due to Stridor in Surgical Intensive Care Patients. Trauma and Acute Care 2016;1(2):11. Disponible en: http:// http://trauma-acute-care.imedpub.com/use-of-steroid-to-prevent-extubation-failure-due-to-stridor-in-surgical-intensive-care-patients.pdf [acceso: 18/09/2018]
26. El-Baradey, Gada F; El-Shmma, Nagat S; Elsharawy, Fatma. Ultrasound-guided laryngeal air column width difference and the cuff leak volume in predciting the effectivensess of steroid therapy on postextubation stridor in adult. Are they useful? Journal of Critical Care 2016;36:272-276. Disponible en: https://sci-hub.tw/https://doi.org/10.1016/j.jcrc.2016.07.007 [acceso: 16/09/2018]
27. Jaber, Samir; Jung, Boris; Chanques, Gérald; Bonnet, Francis; Marret, Emmanuel. Effects of steroids on reintubation and post-extubation stridor in adults: mata-analysis of randomised controlled trails. Critical Care 2009;13(2):R49. Disponible en: https://ccforum.biomedcentral.com/track/pdf/10.1186/cc7772 [acceso: 18/09/2018]

Cómo citar
Esono-Fernández, Elena Cristina; Piñero-Zapata, Manuel; Giménez-Piñero, Consolación; Vera-Corbalán, Catalina. Terapia profiláctica con corticoides en la prevención del edema laríngeo postextubación: Una revisión sistemática. Evidentia. 2019; 16. Disponible en: http://ciberindex.com/c/ev/e12419 [acceso: 06/04/2020]
Revisión Sistemática


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